We have collated some of the latest publications (2021-2022) related directly or indirectly to P. vivax. While this is not an exhaustive list of academic work, we aim to provide a diverse list of reading from across the region and highlight the work of Asia-Pacific researchers.

The publications are categorized four themes: research and development, finance, evidence into policy, and implementation.

Research and development

Under this theme, publications cover areas of further understanding of clinical vivax malaria, improving diagnostics, developing new tools for G6PD screening, and efficacy of current and new radical cure regimens for vivax:

1. Clinical Malaria:
   1. Phyo et al. Clinical impact of vivax malaria: A collection review
2. Malaria Diagnostics:
   1. Pasirabu et al. Comparison of the performance of the CareStart Malaria Pf/Pan Combo test and field microscopy in the diagnosis of Plasmodium vivax malaria in North Sumatera, Indonesia
   2. Das et al. Field evaluation of the diagnostic performance of EasyScan GO: a digital malaria microscopy device based on machine-learning
   3. Longley et al. Plasmodium vivax malaria serological exposure markers: Assessing the degree and implications of cross-reactivity with P. knowlesi
3. G6PD screening:
   1. Zobrist et al. Evaluation of a point-of-care diagnostic to identify glucose-6-phosphate dehydrogenase deficiency in Brazil
   2. Ley et al. Variation in Glucose-6-Phosphate Dehydrogenase activity following acute malaria
   3. Ley et al. Repeatability and reproducibility of a handheld quantitative G6PD diagnostic
4. Blood-stage treatment of vivax malaria:
   1. Soe et al. Therapeutic efficacy of chloroquine for uncomplicated Plasmodium vivax malaria in southeastern and western border areas of Myanmar
   2. Asih et al. Efficacy and safety of dihydroartemisinin–piperaquine for the treatment of uncomplicated Plasmodium falciparum and Plasmodium vivax malaria in Papua and Sumatra, Indonesia
5. Liver-stage treatment of vivax malaria:
   1. Chamma-Siqueira et al. Higher-Dose Primaquine to Prevent Relapse of Plasmodium vivax Malaria
   2. Poespoprodjo et al. Supervised versus unsupervised primaquine radical cure for the treatment of falciparum and vivax malaria in Papua, Indonesia: a cluster-randomised, controlled, open-label superiority trial
   3. Llanos-Cuentas et al. Tafenoquine for the treatment of Plasmodium vivax malaria

       

Finances

This theme includes papers that analyses if the vivax radical cure tools are reasonably priced & affordable:

1. Aung et al. Cost-effectiveness analysis of G6PD diagnostic test for Plasmodium vivax radical cure in Lao PDR: An economic modelling study
2. Brito-Sousa et al. Real-life quantitative G6PD screening in Plasmodium vivax patients in the Brazilian Amazon: A cost-effectiveness analysis
3. Suh et al. Cost-Benefit Analysis of Tafenoquine for Radical Cure of Plasmodium vivax Malaria in Korea

Evidence into policy

Publications under this theme explore the decision-making of policymakers, factors mediating policy change, use of available evidence in policy-making, and remaining challenges:

1. Kaehler et al. Community engagement for malaria elimination in the Greater Mekong Sub-region: a qualitative study among malaria researchers and policymakers
2. Guth et al. Meeting malaria elimination targets and remaining challenges: Qualitative research on perceptions of stakeholders in India and Southeast Asia

    

Implementation

Research that helps us improve implementation of current tools or looks at the feasibility of using new tools, and strategies for reaching un-reached patients in settings where caseloads may be the highest are covered under this theme:

1. Gandrala et al. Recurrence in Plasmodium vivax malaria: a prospective cohort study with long follow-up from a coastal region in South-West India
2. Liu et al. Malaria from hyperendemicity to elimination along international borders in Yunnan, China during 2003‒2020: a case study
3. Loeffel & Ross. The relative impact of interventions on sympatric Plasmodium vivax and Plasmodium falciparum malaria: A systematic review
4. Santos et al. Methods to Assess Adult and Adolescent Patients’ Adherence to Antimalarial Treatment: A Systematic Review
5. Rahmalia et al. Adherence to 14-day radical cure for P. vivax malaria in Papua, Indonesia: a mixed- methods study
6. Anvikar et al. Active Pharmacovigilance for Primaquine Radical Cure of Plasmodium vivax Malaria in Odisha, India