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(i) the establishment of a platform for resource-sharing and effective surveillance-response systems for Asia Pacific and Africa with an initial focus on elimination of lymphatic filariasis, malaria and schistosomiasis;
(ii) development of new strategies, tools and approaches, such as improved diagnostics and antimalarial therapies;
(iii) rigorous validation of surveillance-response systems; and (iv) designing pilot studies to transfer Chinese experiences of successful surveillance-response systems to endemic countries with limited resources.
Inhibition of Plasmepsin V Activity Demonstrates Its Essential Role in Protein Export, PfEMP1 Display, and Survival of Malaria Parasites
The malaria parasite Plasmodium falciparum exports several hundred proteins into the infected erythrocyte that are involved in cellular remodeling and severe virulence. The export mechanism involves the Plasmodium export element (PEXEL), which is a cleavage site for the parasite protease, Plasmepsin V (PMV).
This paper provides the first direct evidence that PMV activity is essential for protein export in Plasmodium spp. and for parasite survival in human erythrocytes and validates PMV as an antimalarial drug target.
This study investigated changes in mosquito net ownership and use following the continued free distribution of LLINs across PNG.
Relative Roles of Weather Variables and Change in Human Population in Malaria: Comparison over Different States of India
A molecular survey of febrile cases in malaria-endemic areas along China-Myanmar border in Yunnan province, People’s Republic of China
Malaria is still a priority public health problem of Nepal where about 84% of the population are at risk.
In this paper, the authors seek to understand how well patients involved in a clinical study of malaria in Bangladesh understand the patient information sheet or the informed consent procedure, or their rights in relation to an uncomplicated malaria study.
A summary of the various topographical, entomological, parasitological, human ecological and socio-economic factors, which are crucial and shape malaria transmission in forested areas, including forested and deforested regions in Asia.
Measuring the path toward malaria elimination: Defining new targets and milestones for from standard surveillance data
A group of authors discuss broadening the definition of malaria elimination to consider appropriate metrics needed to ascertain progress toward malaria elimination.
Challenges in universal coverage and utilization of insecticide-treated bed nets in migrant plantation workers in Myanmar
Read the full free article in Royal Society Biological Sciences.
The Practice of Jhum Cultivation and Its Relationship to Plasmodium falciparum Infection in the Chittagong Hill Districts of Bangladesh
Read the article in American Journal of Tropical Medicine and Hygiene.
Frequently misdiagnosed, Plasmodium knowlesi carries high potential of causing severe or fatal diseases. A large number of naturally acquired human P. knowlesi infections were initiallyreported in the Kapit Division of Sarawak (Malaysia), followed by cases in several geographical regions of Southeast Asia.
This review published in Cell looks at the research on malaria epidemiology and infection-detection technologies, and how they can influence national malaria programs as countries shift tactics and tools from control to elimination.
A comprehensive retrospective study of malaria in Malaysia, including at-risk populations, dominant species, and principal vectors from 200 – 2009.
Download the pdf here.
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