Other News and Resources

Friday
Jul042014

Surveillance-response systems: the key to elimination of tropical diseases

A priority research agenda within a ‘One Health-One World’ frame of global health was developed at The London Declaration on Neglected Tropical Diseases (NTDs), initiated by the World Health Organization. These priorities include;

(i) the establishment of a platform for resource-sharing and effective surveillance-response systems for Asia Pacific and Africa with an initial focus on elimination of lymphatic filariasis, malaria and schistosomiasis;

(ii) development of new strategies, tools and approaches, such as improved diagnostics and antimalarial therapies;

(iii) rigorous validation of surveillance-response systems; and (iv) designing pilot studies to transfer Chinese experiences of successful surveillance-response systems to endemic countries with limited resources.

 

Download the pdf journal article in Infectious Disease of Poverty here. (906 KB)

Wednesday
Jul022014

Inhibition of Plasmepsin V Activity Demonstrates Its Essential Role in Protein Export, PfEMP1 Display, and Survival of Malaria Parasites

The malaria parasite Plasmodium falciparum exports several hundred proteins into the infected erythrocyte that are involved in cellular remodeling and severe virulence. The export mechanism involves the Plasmodium export element (PEXEL), which is a cleavage site for the parasite protease, Plasmepsin V (PMV).

This paper provides the first direct evidence that PMV activity is essential for protein export in Plasmodium spp. and for parasite survival in human erythrocytes and validates PMV as an antimalarial drug target. 

Read the Open Access paper in PLOS Biology here.

Wednesday
Jul022014

NY Times: How to Beat Malaria, Once and For All

Professor of tropical medicine at the University of Oxford and the director of the Shoklo Malaria Research Unit, François H. Nosten, recently penned an Op-Ed in the NY Times entitled, "How to Beat Malaria, Once and For All".

View the online piece here.

Wednesday
Jul022014

Progress in mosquito net coverage in Papua New Guinea

This study investigated changes in mosquito net ownership and use following the continued free distribution of LLINs across PNG.

View/download the Malaria Journal pdf here.

 

Tuesday
Jul012014

Relative Roles of Weather Variables and Change in Human Population in Malaria: Comparison over Different States of India

Malaria depends on vector abundance which, in turn, depends on a combination of weather variables
This paper considered the 28 states of India, characterized by diverse climatic zones and changing population as well as complex variability in malaria, as a natural test bed.
An analysis of potential malaria load was measured based on the number of vector genesis (due to ecological factors), changes in the human population, compared with the reported number of malaria cases. Future research could predict climate change effects on malaria cases.
Wednesday
Jun252014

A molecular survey of febrile cases in malaria-endemic areas along China-Myanmar border in Yunnan province, People’s Republic of China

A molecular survey of febrile patients with a history of traveling abroad along the Myanmar-China endemic border areas from January 2008 to August 2012 was carried out. The rates of infection with species of Plasmodium and compliance of microscopy diagnosis with nested PCR (Polymerase Chain Reaction) results were calculated.
Tuesday
Jun242014

Malaria control in Nepal 1963-2012: challenges on the path towards elimination

 

Malaria is still a priority public health problem of Nepal where about 84% of the population are at risk.

This paper highlights the past and present malaria situation in Nepal and its challenges for long-term malaria elimination strategies.

View/download the Malaria Journal article here.

Wednesday
Jun182014

Participants’ perceptions and understanding of a malaria clinical trial in Bangladesh 

In this paper, the authors seek to understand how well patients involved in a clinical study of malaria in Bangladesh understand the patient information sheet or the informed consent procedure, or their rights in relation to an uncomplicated malaria study.

Read the full text article in Malaria Journal here.


Wednesday
Jun182014

A review of malaria transmission dynamics in forest ecosystems

A summary of the various topographical, entomological, parasitological, human ecological and socio-economic factors, which are crucial and shape malaria transmission in forested areas, including forested and deforested regions in Asia.

View/download the Parasite and Vectors Journal article here.

Wednesday
Jun182014

Measuring the path toward malaria elimination: Defining new targets and milestones for from standard surveillance data 

A group of authors discuss broadening the definition of malaria elimination to consider appropriate metrics needed to ascertain progress toward malaria elimination.

View/download the Science Magazine article pdf here.

Wednesday
Jun182014

Challenges in universal coverage and utilization of insecticide-treated bed nets in migrant plantation workers in Myanmar

The paper addresses issues regarding population of vulnerable, high risk migrant workers. Efforts to improve effective utilization of ITNs provided by continuous mass free distribution, should include durability monitoring, surveillance of insecticide resistance of the vector and behaviour change interventions in migrant plantation workers.

Wednesday
May282014

First Evaluation of Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency in Vivax Malaria Endemic Regions in the Republic of Korea

Wednesday
May282014

Importance of active case detection in a malaria elimination programme

Wednesday
May282014

Asymptomatic Plasmodium falciparum Malaria in Pregnant Women in the Chittagong Hill Districts of Bangladesh 

Wednesday
May142014

The role of vector control in stopping the transmission of malaria: threats and opportunities

Read the full free article in Royal Society Biological Sciences.

 

Wednesday
May142014

The Practice of Jhum Cultivation and Its Relationship to Plasmodium falciparum Infection in the Chittagong Hill Districts of Bangladesh

Monday
May122014

High proportion of knowlesi malaria in recent malaria cases in Malaysia

 

Frequently misdiagnosed, Plasmodium knowlesi carries high potential of causing severe or fatal diseases. A large number of naturally acquired human P. knowlesi infections were initiallyreported in the Kapit Division of Sarawak (Malaysia), followed by cases in several geographical regions of Southeast Asia.

This paper, published May 3 in Malaria Journal investigates the epidemiology of P. knowlesi in Malaysia.
Monday
May122014

The essential role of infection detection technologies for malaria elimination and eradication

This review published in Cell looks at the research on malaria epidemiology and infection-detection technologies, and how they can influence national malaria programs as countries shift tactics and tools from control to elimination.

Download the pdf here.

Monday
May122014

Spatial distribution of malaria in Peninsular Malaysia from 2000 - 2009

A comprehensive retrospective study of malaria in Malaysia, including at-risk populations, dominant species, and principal vectors from 200 – 2009.

Download the pdf here.

Wednesday
Apr232014

Improving the Radical Cure of Plasmodium vivax Malaria

In response to an article, “Efficacy of Three Different Regimens of Primaquine for the Prevention of Relapses of Plasmodium vivax Malaria in the Amazon Basin of Peru” by Durand et al., Professor Ric Price (Menzines Institute for Health Research) offers further insight on a strategies for the safe and reliable radical cure for P. vivax, by using examples outside of Africa.

Read the free full text article here.

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